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Pronuclear transfer

Pronuclear transfer

An innovative method of assisted reproductive technology, in which a man’s sperm, a patient’s oocyte nucleus and a cytoplasm without the donor’s oocyte nucleus are used to create the embryo. With the help of this method, the embryo carries the genetic material of the patients, as well as a small amount of the genetic material of the donor, which is located in the mitochondria of the donor’s oocyte.

Why to chose us

Pronuclear transfer in IVMED

IMED Clinic is one of the few clinics in the world to be the first to introduce the method of pronuclear transfer into practice and use it for the treatment of infertility in IVF programs.
Over the past year, 15 IVF programs, using pronuclear transfer technology, have been successfully carried out in the clinic. 

 

The method is effective:

  • in the treatment of patients with reduced ovarian reserve, when the quality of their own oocytes is insufficient for embryo development
  • in the treatment of patients with mitochondrial diseases (defective mitochondria remain in the cytoplasm of the zygote from the patient’s oocyte from which the nuclei (pronuclei) are received).

Pronuclear transfer in IVMED

IMED Clinic is one of the few clinics in the world to be the first to introduce the method of pronuclear transfer into practice and use it for the treatment of infertility in IVF programs.
Over the past year, 15 IVF programs, using pronuclear transfer technology, have been successfully carried out in the clinic. 

 

The method is effective:

  • in the treatment of patients with reduced ovarian reserve, when the quality of their own oocytes is insufficient for embryo development
  • in the treatment of patients with mitochondrial diseases (defective mitochondria remain in the cytoplasm of the zygote from the patient’s oocyte from which the nuclei (pronuclei) are received).

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The essence of the method

Simultaneously, the partner’s sperm is used for fertilization (ICSI method) of the patient’s oocytes and a similar number of donor oocytes.

At the first stage of embryo development, 2 pronuclei are removed from the zygote obtained from the donor’s oocyte and partner’s sperm and on it’s place 2 pronuclei received from the zygote obtained from the patient’s oocyte and the man’s sperm are transferred.

 

Benefits of Pronuclear Transfer

Please find out more about IVF programs with partial donation of oocytes that use pronuclear transfer technology in the program section (active link to the partial donation section).

The essence of the method

Simultaneously, the partner’s sperm is used for fertilization (ICSI method) of the patient’s oocytes and a similar number of donor oocytes.

At the first stage of embryo development, 2 pronuclei are removed from the zygote obtained from the donor’s oocyte and partner’s sperm and on it’s place 2 pronuclei received from the zygote obtained from the patient’s oocyte and the man’s sperm are transferred.

 

Benefits of Pronuclear Transfer

Please find out more about IVF programs with partial donation of oocytes that use pronuclear transfer technology in the program section (active link to the partial donation section).

All programs

Frequently asked questions

1How can I choose a donor of oocytes?
In order to choose a suitable donor, you should leave a request on our website. Our coordinator will contact you to clarify the parameters of the donor that you are interested in (race, hair color, eye color, body composition, etc.). After that, our specialist will select the candidates who may be suitable for you according to the specified parameters, and send you donor profiles for review, among which you can choose your donor.
2Is it possible to carry out the preparation for embryo transfer at home, without coming to Kyiv?
Yes, you can undergo the medical preparation for embryo transfer in your country, periodically visiting the doctor who will provide you with ultrasound diagnostics. It’s not necessary to come to Kyiv for this.
3How many days will you need to spend in Kyiv during the program?
In order to participate in the donation program with frozen oocytes, it is enough for you and your partner to stay in Kyiv from 1 to 5 days. We will take care of your comfortable stay and provide complete information support.
4 Are pregnancy support medications included in this program?
Pregnancy support medications are already included in this program. You do not have to buy any additional medicines.
5 Can the genetic testing of the embryos be done in this program?
You can use the service of preimplantation genetic testing of embryos for additional fee, since PGT is not included in the program.
6 Will the donor ever learn that she was a donor to us?
The clinic carefully observes the law of Ukraine on the anonymity of donation and will keep the confidentiality of both parties (both the oocyte donor and the couple undergoing treatment).

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Egg donor candidates

150+ comprehensive profiles of egg donors indicating more than 30 characteristics of each donor, including their photos.


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